**Statistical software**

**R packages**- odest_1.1.tar.gz, odest_1.1.zip:
**ODE estimation via RKHS**, R-package that estimates parameters of Ordinary Differential Equations measured with noise by using Reproducing Kernel Hilbert Space (RKHS) approach. - dglars package: R-package for the paper entitiled: "
**Differential geometric least angle regression: a differential geometric approach to sparse generalized linear models**", A. Augugliaro, A. Mineo and E. Wit. - gdglars_1.0.tar.gz:
**gdgLARS**, R-package that calculates a sparse solution path for a Generalized Linear Model with grouped predictors. - neat package: R package associated to the publication: Signorelli, M., Vinciotti, V., Wit, E. C. (2016). "
**NEAT: an efficient network enrichment analysis test**". BMC Bioinformatics, 17:352. - CopulaGGM_1.0.zip:
**Sparse Gaussian Copula Graphical Models**, R-package that calculates a sparse precision matrix for network construction of mixed variables. - gcgmmd_1.0.tar.gz:
**gcgmmd**', R package for sparse Gaussian Copula Graphical Models for mixed variables. - gcgm_1.0.zip:
**Gaussian Copula Graphical Models (GCGM) for mixed variables**, R-package that calculates penalized non-gaussian and/or discrete graphical models. - BDgraph package: R-package for the paper entitiled: "
**Gaussian graphical model determination based on birth-death MCMC inference**", A. Mohammadi and E. Wit. - CGsparse_1.0.zip:
*Biostatistics*, 2013,**Sparse time series chain graphical models for reconstructing genetic networks**, Abegaz and Wit. R-package that calculates sparse autoregressive coefficients and precision matrices. **R3.0**smida_1.0.tar.gz smida_1.1.zip;**R2.15**smida_1.0.tar.gz smida_1.0.zip; :**Statistics for Microarrays**. All the statistical techniques and data described in Statistics for Microarrays have been implemented in the R library smida (under a GNU licence).

- odest_1.1.tar.gz, odest_1.1.zip:
**Data**- CellSignal.zip, CellSignalBin.dat, CellSignalFlat.dat:
**Cell Signalling data**, Data associated with protein flow cytometry data for 11 proteins (Sachs et al, Science, 2005). - mammary-30genes.txt, mammary-30genes.pdf:
**Mammary gland expression data for 30 representative genes**, subset of the data associated with a mammary gland gene expression experiment reported in Wit and McClure (2004) and available in the smida package on CRAN.

- CellSignal.zip, CellSignalBin.dat, CellSignalFlat.dat:
**R code associated with publications**- 2012
- R-code.zip: for the paper entitled: "
**Using mixture of Gamma distributions for Bayesian analysis in an M/G/1 queue with optional second service**", A. Mohammadi, M. Salehi-Rad, E. Wit. - R code (ZIP format) for the paper entitled:
**"Reproducing kernel Hilbert space based estimation of systems of ordinary differential equations"**, Gonzalez, Vujacic and Wit. - R code (ZIP format) for the paper entitled:
**"A new statistical framework to infer gene regulatory networks with hidden transcription factors"**, Gonzalez, Vujacic and Wit. - R-Code.zip: for the paper entitled:
**"State-space modeling of dynamic genetic networks"**, A.Lotsi, and E.Wit. - R-Code.zip: for the paper entitled:
**"Network estimation in State Space Model with L1-regularization constraint"**, A.Lotsi, and E.Wit. - R-Code.zip, Data.zip:
**"Probability genotype imputation method and integrated weighted adaptive lasso for QTL identification."**Demetrashvili N., Van den Heuvel E.R. and Wit E.C. - FriendshipData.txt: Data belonging to
**"Is it chaos? No just a mess!"**, FMF Almanak 2012. Consists of 30 opinion polls scores (normalized) measured on 8 individuals.

- R-code.zip: for the paper entitled: "